BDBM289090 Methyl-[(1S)-2-[4-[2-[4-amino-6-methyl-2-(trifluoromethyl)pyrimidin-5-yl]ethyl]-1-piperidyl]-1-methyl-2-oxo-ethyl]carbamate::US10093651, Example 20

SMILES: COC(=O)N[C@@H](C)C(=O)N1CCC(CCc2c(C)nc(nc2N)C(F)(F)F)CC1

InChI Key: InChIKey=DKDJHOHQFAHDLU-NSHDSACASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289090   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin O-acyltransferase (Homo sapiens (Human))	BDBM289090 (Methyl-[(1S)-2-[4-[2-[4-amino-6-methyl-2-(trifluor...) Show SMILES COC(=O)N[C@@H](C)C(=O)N1CCC(CCc2c(C)nc(nc2N)C(F)(F)F)CC1 |r| Show InChI InChI=1S/C18H26F3N5O3/c1-10-13(14(22)25-16(23-10)18(19,20)21)5-4-12-6-8-26(9-7-12)15(27)11(2)24-17(28)29-3/h11-12H,4-9H2,1-3H3,(H,24,28)(H2,22,23,25)/t11-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	615	n/a	n/a	n/a	n/a	7.5	n/a
Eli Lilly and Company US Patent					Assay Description Prepare test compounds in DMSO to make up a 0.2 mM stock solution. Serially dilute the stock solution in DMSO to obtain a ten-point dilution curve wi...				US Patent US10093651 (2018) BindingDB Entry DOI: 10.7270/Q2XG9T5D
					More data for this Ligand-Target Pair