BDBM290400 (3R,4S)-3-amino-4-(3-boronopropyl)-1-((1-methylpiperidin-2- yl)methyl)pyrrolidine-3-carboxylic acid::US10098902, Example 36::US10603330, Example 36

SMILES: CN1CCCCC1CN1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O

InChI Key: InChIKey=OSECEHSICOZXIT-YOYPFHDYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 290400   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arginase-1 (Homo sapiens (Human))	BDBM290400 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-((1-methylpip...) Show SMILES CN1CCCCC1CN1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O |r| Show InChI InChI=1S/C15H30BN3O4/c1-18-8-3-2-6-13(18)10-19-9-12(5-4-7-16(22)23)15(17,11-19)14(20)21/h12-13,22-23H,2-11,17H2,1H3,(H,20,21)/t12-,13?,15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM290400 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-((1-methylpip...) Show SMILES CN1CCCCC1CN1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O |r| Show InChI InChI=1S/C15H30BN3O4/c1-18-8-3-2-6-13(18)10-19-9-12(5-4-7-16(22)23)15(17,11-19)14(20)21/h12-13,22-23H,2-11,17H2,1H3,(H,20,21)/t12-,13?,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10603330 (2020)
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290400 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-((1-methylpip...) Show SMILES CN1CCCCC1CN1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O |r| Show InChI InChI=1S/C15H30BN3O4/c1-18-8-3-2-6-13(18)10-19-9-12(5-4-7-16(22)23)15(17,11-19)14(20)21/h12-13,22-23H,2-11,17H2,1H3,(H,20,21)/t12-,13?,15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10603330 (2020)
					More data for this Ligand-Target Pair
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM290400 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-((1-methylpip...) Show SMILES CN1CCCCC1CN1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O |r| Show InChI InChI=1S/C15H30BN3O4/c1-18-8-3-2-6-13(18)10-19-9-12(5-4-7-16(22)23)15(17,11-19)14(20)21/h12-13,22-23H,2-11,17H2,1H3,(H,20,21)/t12-,13?,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	625	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair