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SMILES: Cc1cc(F)ncc1-c1cnc2nc(COc3ccccc3)cn2c1

InChI Key: InChIKey=WUOFCJKPYKXEBX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 292183   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM292183 (US10100057, Example 38 | US11046702, Example 38 | ...) Show SMILES Cc1cc(F)ncc1-c1cnc2nc(COc3ccccc3)cn2c1 Show InChI InChI=1S/C19H15FN4O/c1-13-7-18(20)21-9-17(13)14-8-22-19-23-15(11-24(19)10-14)12-25-16-5-3-2-4-6-16/h2-11H,12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	25
SK BIOPHARMACEUTICALS CO., LTD. US Patent					Assay Description Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...				US Patent US10100057 (2018) BindingDB Entry DOI: 10.7270/Q2028TKW
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM292183 (US10100057, Example 38 | US11046702, Example 38 | ...) Show SMILES Cc1cc(F)ncc1-c1cnc2nc(COc3ccccc3)cn2c1 Show InChI InChI=1S/C19H15FN4O/c1-13-7-18(20)21-9-17(13)14-8-22-19-23-15(11-24(19)10-14)12-25-16-5-3-2-4-6-16/h2-11H,12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM292183 (US10100057, Example 38 | US11046702, Example 38 | ...) Show SMILES Cc1cc(F)ncc1-c1cnc2nc(COc3ccccc3)cn2c1 Show InChI InChI=1S/C19H15FN4O/c1-13-7-18(20)21-9-17(13)14-8-22-19-23-15(11-24(19)10-14)12-25-16-5-3-2-4-6-16/h2-11H,12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
SK BIOPHARMACEUTICALS CO., LTD. US Patent					Assay Description Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...				US Patent US9745310 (2017) BindingDB Entry DOI: 10.7270/Q24T6MG4
					More data for this Ligand-Target Pair