null

SMILES: Fc1ccc(OCc2cn3cc(cnc3n2)-c2ccc(F)cc2F)cc1

InChI Key: InChIKey=VZWZRMZAYXRWAP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 292192   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM292192 (US10100057, Example 47 | US11046702, Example 47 | ...) Show SMILES Fc1ccc(OCc2cn3cc(cnc3n2)-c2ccc(F)cc2F)cc1 Show InChI InChI=1S/C19H12F3N3O/c20-13-1-4-16(5-2-13)26-11-15-10-25-9-12(8-23-19(25)24-15)17-6-3-14(21)7-18(17)22/h1-10H,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	25
SK BIOPHARMACEUTICALS CO., LTD. US Patent					Assay Description Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...				US Patent US10100057 (2018) BindingDB Entry DOI: 10.7270/Q2028TKW
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM292192 (US10100057, Example 47 | US11046702, Example 47 | ...) Show SMILES Fc1ccc(OCc2cn3cc(cnc3n2)-c2ccc(F)cc2F)cc1 Show InChI InChI=1S/C19H12F3N3O/c20-13-1-4-16(5-2-13)26-11-15-10-25-9-12(8-23-19(25)24-15)17-6-3-14(21)7-18(17)22/h1-10H,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM292192 (US10100057, Example 47 | US11046702, Example 47 | ...) Show SMILES Fc1ccc(OCc2cn3cc(cnc3n2)-c2ccc(F)cc2F)cc1 Show InChI InChI=1S/C19H12F3N3O/c20-13-1-4-16(5-2-13)26-11-15-10-25-9-12(8-23-19(25)24-15)17-6-3-14(21)7-18(17)22/h1-10H,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
SK BIOPHARMACEUTICALS CO., LTD. US Patent					Assay Description Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...				US Patent US9745310 (2017) BindingDB Entry DOI: 10.7270/Q24T6MG4
					More data for this Ligand-Target Pair