BDBM29656 4-[(Pyridin-3-ylmethyl)-amino]-2,3-dihydro-1H-4a,9-diaza-cyclopenta[b]fluorene-10-carbonitrile::MLS000556361::SMR000147678::cid_702038

SMILES: N#Cc1c2CCCc2c(NCc2cccnc2)n2c1nc1ccccc21

InChI Key: InChIKey=GYVDMWVPDNIPMH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29656   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Runt-related transcription factor 1 (Homo sapiens (Human))	BDBM29656 (4-[(Pyridin-3-ylmethyl)-amino]-2,3-dihydro-1H-4a,9...) Show SMILES N#Cc1c2CCCc2c(NCc2cccnc2)n2c1nc1ccccc21 Show InChI InChI=1S/C21H17N5/c22-11-17-15-6-3-7-16(15)20(24-13-14-5-4-10-23-12-14)26-19-9-2-1-8-18(19)25-21(17)26/h1-2,4-5,8-10,12,24H,3,6-7,13H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.35E+4	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX
					More data for this Ligand-Target Pair
Runt-related transcription factor 1 (Homo sapiens (Human))	BDBM29656 (4-[(Pyridin-3-ylmethyl)-amino]-2,3-dihydro-1H-4a,9...) Show SMILES N#Cc1c2CCCc2c(NCc2cccnc2)n2c1nc1ccccc21 Show InChI InChI=1S/C21H17N5/c22-11-17-15-6-3-7-16(15)20(24-13-14-5-4-10-23-12-14)26-19-9-2-1-8-18(19)25-21(17)26/h1-2,4-5,8-10,12,24H,3,6-7,13H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.35E+4	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P
					More data for this Ligand-Target Pair