BDBM29667 3-Amino-6,7,8,9-tetrahydro-5H-1-thia-10-aza-cyclohepta[f]indene-2-carboxylic acid (5-ethyl-[1,3,4]thiadiazol-2-yl)-amide::MLS000559672::SMR000177982::cid_2059585

SMILES: CCc1nnc(NC(=O)c2sc3nc4CCCCCc4cc3c2N)s1

InChI Key: InChIKey=BYNBYSXFLMGCQK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29667   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Runt-related transcription factor 1 (Homo sapiens (Human))	BDBM29667 (3-Amino-6,7,8,9-tetrahydro-5H-1-thia-10-aza-cycloh...) Show SMILES CCc1nnc(NC(=O)c2sc3nc4CCCCCc4cc3c2N)s1 Show InChI InChI=1S/C17H19N5OS2/c1-2-12-21-22-17(24-12)20-15(23)14-13(18)10-8-9-6-4-3-5-7-11(9)19-16(10)25-14/h8H,2-7,18H2,1H3,(H,20,22,23)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.66E+4	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX
					More data for this Ligand-Target Pair
Runt-related transcription factor 1 (Homo sapiens (Human))	BDBM29667 (3-Amino-6,7,8,9-tetrahydro-5H-1-thia-10-aza-cycloh...) Show SMILES CCc1nnc(NC(=O)c2sc3nc4CCCCCc4cc3c2N)s1 Show InChI InChI=1S/C17H19N5OS2/c1-2-12-21-22-17(24-12)20-15(23)14-13(18)10-8-9-6-4-3-5-7-11(9)19-16(10)25-14/h8H,2-7,18H2,1H3,(H,20,22,23)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.66E+4	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P
					More data for this Ligand-Target Pair