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SMILES: Cn1cnc2ccc(cc12)-c1cccc(OC[C@@H](O)CN2Cc3ccccc3C2)c1

InChI Key: InChIKey=WQQGWPMSSVHIRU-QFIPXVFZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297735   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM297735 (US10118918, Compound 14 | US9732072, Compound 14) Show SMILES Cn1cnc2ccc(cc12)-c1cccc(OC[C@@H](O)CN2Cc3ccccc3C2)c1 |r| Show InChI InChI=1S/C25H25N3O2/c1-27-17-26-24-10-9-19(12-25(24)27)18-7-4-8-23(11-18)30-16-22(29)15-28-13-20-5-2-3-6-21(20)14-28/h2-12,17,22,29H,13-16H2,1H3/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description General Materials.S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), bicine, KCl, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG)...				US Patent US9732072 (2017) BindingDB Entry DOI: 10.7270/Q2FF3VGW
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM297735 (US10118918, Compound 14 | US9732072, Compound 14) Show SMILES Cn1cnc2ccc(cc12)-c1cccc(OC[C@@H](O)CN2Cc3ccccc3C2)c1 |r| Show InChI InChI=1S/C25H25N3O2/c1-27-17-26-24-10-9-19(12-25(24)27)18-7-4-8-23(11-18)30-16-22(29)15-28-13-20-5-2-3-6-21(20)14-28/h2-12,17,22,29H,13-16H2,1H3/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10118918 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZK6
					More data for this Ligand-Target Pair