BDBM298362 US10124003, Ex. Compound 28::US10835536, Ex. Comp 28::US10894048, Ex Comp 28

SMILES: COc1cc(OC)cc(c1)C#Cc1nn([C@H]2C[C@@H](CO)N(C2)C(=O)C=C)c2ncnc(N)c12

InChI Key: InChIKey=FJYGEUHEYMHEHG-HOTGVXAUSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 298362   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM298362 (US10124003, Ex. Compound 28 | US10835536, Ex. Comp...) Show SMILES COc1cc(OC)cc(c1)C#Cc1nn([C@H]2C[C@@H](CO)N(C2)C(=O)C=C)c2ncnc(N)c12 |r| Show InChI InChI=1S/C23H24N6O4/c1-4-20(31)28-11-15(9-16(28)12-30)29-23-21(22(24)25-13-26-23)19(27-29)6-5-14-7-17(32-2)10-18(8-14)33-3/h4,7-8,10,13,15-16,30H,1,9,11-12H2,2-3H3,(H2,24,25,26)/t15-,16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10124003 (2018) BindingDB Entry DOI: 10.7270/Q2B27XBQ
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM298362 (US10124003, Ex. Compound 28 | US10835536, Ex. Comp...) Show SMILES COc1cc(OC)cc(c1)C#Cc1nn([C@H]2C[C@@H](CO)N(C2)C(=O)C=C)c2ncnc(N)c12 |r| Show InChI InChI=1S/C23H24N6O4/c1-4-20(31)28-11-15(9-16(28)12-30)29-23-21(22(24)25-13-26-23)19(27-29)6-5-14-7-17(32-2)10-18(8-14)33-3/h4,7-8,10,13,15-16,30H,1,9,11-12H2,2-3H3,(H2,24,25,26)/t15-,16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10894048 (2021)
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM298362 (US10124003, Ex. Compound 28 | US10835536, Ex. Comp...) Show SMILES COc1cc(OC)cc(c1)C#Cc1nn([C@H]2C[C@@H](CO)N(C2)C(=O)C=C)c2ncnc(N)c12 |r| Show InChI InChI=1S/C23H24N6O4/c1-4-20(31)28-11-15(9-16(28)12-30)29-23-21(22(24)25-13-26-23)19(27-29)6-5-14-7-17(32-2)10-18(8-14)33-3/h4,7-8,10,13,15-16,30H,1,9,11-12H2,2-3H3,(H2,24,25,26)/t15-,16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10835536 (2020)
					More data for this Ligand-Target Pair