BDBM300759 US10130642, Example 6-19

SMILES: CC(CO)(CC(Cc1ccc(cc1)-c1ccccc1)NC(=O)C1CC(O)=NO1)C(O)=O

InChI Key: InChIKey=LLSSZLRHRKIFRQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300759   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM300759 (US10130642, Example 6-19) Show SMILES CC(CO)(CC(Cc1ccc(cc1)-c1ccccc1)NC(=O)C1CC(O)=NO1)C(O)=O |c:27| Show InChI InChI=1S/C23H26N2O6/c1-23(14-26,22(29)30)13-18(24-21(28)19-12-20(27)25-31-19)11-15-7-9-17(10-8-15)16-5-3-2-4-6-16/h2-10,18-19,26H,11-14H2,1H3,(H,24,28)(H,25,27)(H,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THERAVANCE BIOPHARMA R&D IP, LLC US Patent					Assay Description Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...				US Patent US10130642 (2018) BindingDB Entry DOI: 10.7270/Q29Z96ZH
					More data for this Ligand-Target Pair