BDBM301702 US10131692, Compound 34
SMILES: CCNC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H]1CSCN1C(=O)[C@@H]1CSCCC(=O)N[C@@H](Cc2ccc(Cl)cc2)C(=O)N[C@@H](Cc2cccs2)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N1
InChI Key: InChIKey=PJAUPEPLVJQOFW-UMHAZJGASA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vasopressin V1b receptor (Homo sapiens (Human)) | BDBM301702![]() (US10131692, Compound 34) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 4.02E+4 | n/a | n/a | n/a | n/a |
Ferring B.V. US Patent | Assay Description To determine selectivity, compounds were tested in luciferase-based transcriptional reporter gene assays expressing the human V1b receptor (hV1bR). A... | US Patent US10131692 (2018) BindingDB Entry DOI: 10.7270/Q2WQ05TR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM301702![]() (US10131692, Compound 34) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a |
Ferring B.V. US Patent | Assay Description Agonist activity of compounds on the human V2 receptor (h V2R) was determined in a transcriptional reporter gene assay by transiently transfecting an... | US Patent US10131692 (2018) BindingDB Entry DOI: 10.7270/Q2WQ05TR | |||||||||||
More data for this Ligand-Target Pair |