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BDBM301750 US9597310, 40::{(S)-6-[(R)-4-(4-bromo-phenoxy)-7-fluoro-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester

SMILES: COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c3c(F)ccc4Oc3ccc(Br)cc3)ccc12

InChI Key: InChIKey=QAMWZIPFBCUUEC-IQMFZBJNSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301750   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM301750
PNG
(US9597310, 40 | {(S)-6-[(R)-4-(4-bromo-phenoxy)-7-...)
Show SMILES COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c3c(F)ccc4Oc3ccc(Br)cc3)ccc12 |r|
Show InChI InChI=1S/C26H22BrFO5/c1-30-25(29)12-15-14-31-24-13-18(6-7-19(15)24)33-23-10-8-20-22(11-9-21(28)26(20)23)32-17-4-2-16(27)3-5-17/h2-7,9,11,13,15,23H,8,10,12,14H2,1H3/t15-,23-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 733n/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
IP1 accumulation measurements using the IPOne assay system 1321N1 cells stably expressing human GPR40 receptor (Euroscreen, Belgium) are seeded 24 h ...

US Patent US9597310 (2017)


BindingDB Entry DOI: 10.7270/Q2RX9F3W
More data for this
Ligand-Target Pair