BDBM301757 ((S)-6-{(R)-4-[2-Cyano-4-(3-hydroxy-3-methylbutoxy)phenoxy]-7-fluoro-indan-1-yloxy}-2,3-dihydrobenzofuran-3-yl)-acetic acid::US9597310, 47

SMILES: CC(C)(O)CCOc1ccc(Oc2ccc(F)c3[C@@H](CCc23)Oc2ccc3[C@H](CC(O)=O)COc3c2)c(c1)C#N

InChI Key: InChIKey=IZOAMFOTMPCTER-XHCCPWGMSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM301757 (((S)-6-{(R)-4-[2-Cyano-4-(3-hydroxy-3-methylbutoxy...) Show SMILES CC(C)(O)CCOc1ccc(Oc2ccc(F)c3[C@@H](CCc23)Oc2ccc3[C@H](CC(O)=O)COc3c2)c(c1)C#N |r| Show InChI InChI=1S/C31H30FNO7/c1-31(2,36)11-12-37-20-4-8-25(18(13-20)16-33)40-26-10-7-24(32)30-23(26)6-9-27(30)39-21-3-5-22-19(14-29(34)35)17-38-28(22)15-21/h3-5,7-8,10,13,15,19,27,36H,6,9,11-12,14,17H2,1-2H3,(H,34,35)/t19-,27-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description IP1 accumulation measurements using the IPOne assay system 1321N1 cells stably expressing human GPR40 receptor (Euroscreen, Belgium) are seeded 24 h ...				US Patent US9597310 (2017) BindingDB Entry DOI: 10.7270/Q2RX9F3W
					More data for this Ligand-Target Pair