null

SMILES:

InChI Key: InChIKey=VIMWDHWGZRSDLZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 302007   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM302007 (US9598405, 2.6) Show SMILES Show InChI InChI=1S/C26H29N7O3S/c1-4-36-24(34)17-5-8-26(35,9-6-17)25-28-15-21(37-25)19-11-16(2)12-23(30-19)31-22-13-18(7-10-27-22)20-14-29-33(3)32-20/h7,10-15,17,35H,4-6,8-9H2,1-3H3,(H,27,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.47	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...				US Patent US9598405 (2017) BindingDB Entry DOI: 10.7270/Q2BR8V7T
					More data for this Ligand-Target Pair