BDBM30232 carboline analog, 44

SMILES: CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccccc1F

InChI Key: InChIKey=VRSXQRFFXZUSGP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30232   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAPK-Activated Protein Kinase 2 (MK2) (Homo sapiens (Human))	BDBM30232 (carboline analog, 44) Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccccc1F Show InChI InChI=1S/C19H16FN3O2/c1-10-9-21-19(25)17-16(10)12-8-11(6-7-14(12)22-17)18(24)23-15-5-3-2-4-13(15)20/h2-8,10,22H,9H2,1H3,(H,21,25)(H,23,24)	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	7.6	25
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...				Bioorg Med Chem Lett 17: 4664-9 (2007) Article DOI: 10.1016/j.bmcl.2007.05.101 BindingDB Entry DOI: 10.7270/Q23N21QP
					More data for this Ligand-Target Pair