BDBM30242 carboline analog, 54

SMILES: CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1cccc(c1)C#N

InChI Key: InChIKey=BWMYAAGVSXHFLF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30242   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAPK-Activated Protein Kinase 2 (MK2) (Homo sapiens (Human))	BDBM30242 (carboline analog, 54) Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1cccc(c1)C#N Show InChI InChI=1S/C20H16N4O2/c1-11-10-22-20(26)18-17(11)15-8-13(5-6-16(15)24-18)19(25)23-14-4-2-3-12(7-14)9-21/h2-8,11,24H,10H2,1H3,(H,22,26)(H,23,25)	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...				Bioorg Med Chem Lett 17: 4664-9 (2007) Article DOI: 10.1016/j.bmcl.2007.05.101 BindingDB Entry DOI: 10.7270/Q23N21QP
					More data for this Ligand-Target Pair