null

SMILES: NC(=O)c1c2CN(CCn2nc1-c1ccc(F)cc1)C(=O)NC1CCCCC1

InChI Key: InChIKey=ACCUWCZOHGIQFN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM302436 (N5-Cyclohexyl-2-(4-fluorophenyl)-6,7- dihydropyraz...) Show SMILES NC(=O)c1c2CN(CCn2nc1-c1ccc(F)cc1)C(=O)NC1CCCCC1 Show InChI InChI=1S/C20H24FN5O2/c21-14-8-6-13(7-9-14)18-17(19(22)27)16-12-25(10-11-26(16)24-18)20(28)23-15-4-2-1-3-5-15/h6-9,15H,1-5,10-12H2,(H2,22,27)(H,23,28)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9598423 (2017) BindingDB Entry DOI: 10.7270/Q2FJ2JT9
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM302436 (N5-Cyclohexyl-2-(4-fluorophenyl)-6,7- dihydropyraz...) Show SMILES NC(=O)c1c2CN(CCn2nc1-c1ccc(F)cc1)C(=O)NC1CCCCC1 Show InChI InChI=1S/C20H24FN5O2/c21-14-8-6-13(7-9-14)18-17(19(22)27)16-12-25(10-11-26(16)24-18)20(28)23-15-4-2-1-3-5-15/h6-9,15H,1-5,10-12H2,(H2,22,27)(H,23,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9598423 (2017) BindingDB Entry DOI: 10.7270/Q2FJ2JT9
					More data for this Ligand-Target Pair