BDBM30247 carboline analog, 59

SMILES: CC(C)c1ccc(NC(=O)c2ccc3[nH]c4c(C(C)CNC4=O)c3c2)cc1

InChI Key: InChIKey=HMEVETSOKVZITQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30247   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAPK-Activated Protein Kinase 2 (MK2) (Homo sapiens (Human))	BDBM30247 (carboline analog, 59) Show SMILES CC(C)c1ccc(NC(=O)c2ccc3[nH]c4c(C(C)CNC4=O)c3c2)cc1 Show InChI InChI=1S/C22H23N3O2/c1-12(2)14-4-7-16(8-5-14)24-21(26)15-6-9-18-17(10-15)19-13(3)11-23-22(27)20(19)25-18/h4-10,12-13,25H,11H2,1-3H3,(H,23,27)(H,24,26)	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...				Bioorg Med Chem Lett 17: 4664-9 (2007) Article DOI: 10.1016/j.bmcl.2007.05.101 BindingDB Entry DOI: 10.7270/Q23N21QP
					More data for this Ligand-Target Pair