BDBM30256 carboline analog, 68

SMILES: COC(=O)c1ccc(NC(=O)c2ccc3[nH]c4c(C(C)CNC4=O)c3c2)cn1

InChI Key: InChIKey=BOMJDFMGBLZPOK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30256   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAPK-Activated Protein Kinase 2 (MK2) (Homo sapiens (Human))	BDBM30256 (carboline analog, 68) Show SMILES COC(=O)c1ccc(NC(=O)c2ccc3[nH]c4c(C(C)CNC4=O)c3c2)cn1 Show InChI InChI=1S/C20H18N4O4/c1-10-8-22-19(26)17-16(10)13-7-11(3-5-14(13)24-17)18(25)23-12-4-6-15(21-9-12)20(27)28-2/h3-7,9-10,24H,8H2,1-2H3,(H,22,26)(H,23,25)	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...				Bioorg Med Chem Lett 17: 4664-9 (2007) Article DOI: 10.1016/j.bmcl.2007.05.101 BindingDB Entry DOI: 10.7270/Q23N21QP
					More data for this Ligand-Target Pair