BDBM30260 carboline analog, 72

SMILES: COC(=O)c1cnc(NC(=O)c2ccc3[nH]c4c(C(C)CNC4=O)c3c2)s1

InChI Key: InChIKey=MFUFGIWZXLEILE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30260   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAPK-Activated Protein Kinase 2 (MK2) (Homo sapiens (Human))	BDBM30260 (carboline analog, 72) Show SMILES COC(=O)c1cnc(NC(=O)c2ccc3[nH]c4c(C(C)CNC4=O)c3c2)s1 Show InChI InChI=1S/C18H16N4O4S/c1-8-6-19-16(24)14-13(8)10-5-9(3-4-11(10)21-14)15(23)22-18-20-7-12(27-18)17(25)26-2/h3-5,7-8,21H,6H2,1-2H3,(H,19,24)(H,20,22,23)	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...				Bioorg Med Chem Lett 17: 4664-9 (2007) Article DOI: 10.1016/j.bmcl.2007.05.101 BindingDB Entry DOI: 10.7270/Q23N21QP
					More data for this Ligand-Target Pair