BDBM30261 carboline analog, 73

SMILES: CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ncc(s1)C(N)=O

InChI Key: InChIKey=BTHFDMHVCJFREX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAPK-Activated Protein Kinase 2 (MK2) (Homo sapiens (Human))	BDBM30261 (carboline analog, 73) Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ncc(s1)C(N)=O Show InChI InChI=1S/C17H15N5O3S/c1-7-5-19-16(25)13-12(7)9-4-8(2-3-10(9)21-13)15(24)22-17-20-6-11(26-17)14(18)23/h2-4,6-7,21H,5H2,1H3,(H2,18,23)(H,19,25)(H,20,22,24)	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...				Bioorg Med Chem Lett 17: 4664-9 (2007) Article DOI: 10.1016/j.bmcl.2007.05.101 BindingDB Entry DOI: 10.7270/Q23N21QP
					More data for this Ligand-Target Pair