null

SMILES: NC(=O)c1c2CN(CCn2nc1-c1ccc(Cl)c(Cl)c1)C(=O)Nc1ccc2ccncc2c1

InChI Key: InChIKey=MBTMPQASTKJMDH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302643   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM302643 (2-(3,4-Dichlorophenyl)-N5- (isoquinolin-7-yl)-6,7-...) Show SMILES NC(=O)c1c2CN(CCn2nc1-c1ccc(Cl)c(Cl)c1)C(=O)Nc1ccc2ccncc2c1 |$;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;$| Show InChI InChI=1S/C23H18Cl2N6O2/c24-17-4-2-14(10-18(17)25)21-20(22(26)32)19-12-30(7-8-31(19)29-21)23(33)28-16-3-1-13-5-6-27-11-15(13)9-16/h1-6,9-11H,7-8,12H2,(H2,26,32)(H,28,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9598423 (2017) BindingDB Entry DOI: 10.7270/Q2FJ2JT9
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM302643 (2-(3,4-Dichlorophenyl)-N5- (isoquinolin-7-yl)-6,7-...) Show SMILES NC(=O)c1c2CN(CCn2nc1-c1ccc(Cl)c(Cl)c1)C(=O)Nc1ccc2ccncc2c1 |$;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;$| Show InChI InChI=1S/C23H18Cl2N6O2/c24-17-4-2-14(10-18(17)25)21-20(22(26)32)19-12-30(7-8-31(19)29-21)23(33)28-16-3-1-13-5-6-27-11-15(13)9-16/h1-6,9-11H,7-8,12H2,(H2,26,32)(H,28,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9598423 (2017) BindingDB Entry DOI: 10.7270/Q2FJ2JT9
					More data for this Ligand-Target Pair