null

SMILES: Cc1cc(F)cc(c1)-c1nn2CCN(Cc2c1C(N)=O)C(=O)Nc1ccc2OC(F)(F)Oc2c1

InChI Key: InChIKey=KPORKOAJVIFSTI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302659   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM302659 (N5-(2,2-Difluorobenzo[d] [1,3]dioxol-5-yl)-2-(3- f...) Show SMILES Cc1cc(F)cc(c1)-c1nn2CCN(Cc2c1C(N)=O)C(=O)Nc1ccc2OC(F)(F)Oc2c1 |$;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;$| Show InChI InChI=1S/C22H18F3N5O4/c1-11-6-12(8-13(23)7-11)19-18(20(26)31)15-10-29(4-5-30(15)28-19)21(32)27-14-2-3-16-17(9-14)34-22(24,25)33-16/h2-3,6-9H,4-5,10H2,1H3,(H2,26,31)(H,27,32)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9598423 (2017) BindingDB Entry DOI: 10.7270/Q2FJ2JT9
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM302659 (N5-(2,2-Difluorobenzo[d] [1,3]dioxol-5-yl)-2-(3- f...) Show SMILES Cc1cc(F)cc(c1)-c1nn2CCN(Cc2c1C(N)=O)C(=O)Nc1ccc2OC(F)(F)Oc2c1 |$;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;$| Show InChI InChI=1S/C22H18F3N5O4/c1-11-6-12(8-13(23)7-11)19-18(20(26)31)15-10-29(4-5-30(15)28-19)21(32)27-14-2-3-16-17(9-14)34-22(24,25)33-16/h2-3,6-9H,4-5,10H2,1H3,(H2,26,31)(H,27,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9598423 (2017) BindingDB Entry DOI: 10.7270/Q2FJ2JT9
					More data for this Ligand-Target Pair