BDBM30270 carboline analog, 82

SMILES: CCCNC(=O)c1csc(NC(=O)c2ccc3[nH]c4c(C(C)CNC4=O)c3c2)n1

InChI Key: InChIKey=LZBQQQTVRKBMOH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30270   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAPK-Activated Protein Kinase 2 (MK2) (Homo sapiens (Human))	BDBM30270 (carboline analog, 82) Show SMILES CCCNC(=O)c1csc(NC(=O)c2ccc3[nH]c4c(C(C)CNC4=O)c3c2)n1 Show InChI InChI=1S/C20H21N5O3S/c1-3-6-21-18(27)14-9-29-20(24-14)25-17(26)11-4-5-13-12(7-11)15-10(2)8-22-19(28)16(15)23-13/h4-5,7,9-10,23H,3,6,8H2,1-2H3,(H,21,27)(H,22,28)(H,24,25,26)	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...				Bioorg Med Chem Lett 17: 4664-9 (2007) Article DOI: 10.1016/j.bmcl.2007.05.101 BindingDB Entry DOI: 10.7270/Q23N21QP
					More data for this Ligand-Target Pair				3D Structure (docked)