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SMILES: CNCC1Cn2c(cc3ccc(cc23)C(=O)Nc2nccs2)C(=O)N1

InChI Key: InChIKey=KVHNFEISHHCIEZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30292   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
MAP kinase-activated protein kinase 2 [41-364]


(Homo sapiens (Human))		BDBM30292
PNG
(indole-based 6-membered lactam, 4f)
Show SMILES CNCC1Cn2c(cc3ccc(cc23)C(=O)Nc2nccs2)C(=O)N1
Show InChI InChI=1S/C17H17N5O2S/c1-18-8-12-9-22-13-7-11(15(23)21-17-19-4-5-25-17)3-2-10(13)6-14(22)16(24)20-12/h2-7,12,18H,8-9H2,1H3,(H,20,24)(H,19,21,23)
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MMDB

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Similars
Article
PubMed
n/an/a 580n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...

Bioorg Med Chem Lett 18: 1994-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.119
BindingDB Entry DOI: 10.7270/Q2ZW1J8V
More data for this
Ligand-Target Pair