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SMILES: CC(C)NCC1Cn2c(cc3ccc(cc23)C(=O)Nc2nccs2)C(=O)N1

InChI Key: InChIKey=CEDLSFPRHQTGPW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30295   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
MAP kinase-activated protein kinase 2 [41-364]


(Homo sapiens (Human))		BDBM30295
PNG
(indole-based 6-membered lactam, 4i)
Show SMILES CC(C)NCC1Cn2c(cc3ccc(cc23)C(=O)Nc2nccs2)C(=O)N1
Show InChI InChI=1S/C19H21N5O2S/c1-11(2)21-9-14-10-24-15-8-13(17(25)23-19-20-5-6-27-19)4-3-12(15)7-16(24)18(26)22-14/h3-8,11,14,21H,9-10H2,1-2H3,(H,22,26)(H,20,23,25)
PDB
MMDB

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Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...

Bioorg Med Chem Lett 18: 1994-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.119
BindingDB Entry DOI: 10.7270/Q2ZW1J8V
More data for this
Ligand-Target Pair