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SMILES: CCNCC1CNC(=O)c2cc3ccc(cc3n2C1)C(=O)Nc1nccs1

InChI Key: InChIKey=XQZOZIZDEUGUED-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30306   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
MAP kinase-activated protein kinase 2 [41-364]


(Homo sapiens (Human))		BDBM30306
PNG
(indole-based 7-membered lactam, 25g)
Show SMILES CCNCC1CNC(=O)c2cc3ccc(cc3n2C1)C(=O)Nc1nccs1
Show InChI InChI=1S/C19H21N5O2S/c1-2-20-9-12-10-22-18(26)16-7-13-3-4-14(8-15(13)24(16)11-12)17(25)23-19-21-5-6-27-19/h3-8,12,20H,2,9-11H2,1H3,(H,22,26)(H,21,23,25)
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Article
PubMed
n/an/a 560n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...

Bioorg Med Chem Lett 18: 1994-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.119
BindingDB Entry DOI: 10.7270/Q2ZW1J8V
More data for this
Ligand-Target Pair