null

SMILES: CCn1nnc2c(C)c(ccc12)C(CC(O)=O)c1ccc(C)c(CN2C[C@@H](C)Oc3ncccc3S2(=O)=O)c1

InChI Key: InChIKey=IOXXTPJNZJWFCO-FKSKYRLFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 304752   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kelch-like ECH-associated protein 1 [321-609] (Homo sapiens (Human))	BDBM304752 (3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl...) Show SMILES CCn1nnc2c(C)c(ccc12)C(CC(O)=O)c1ccc(C)c(CN2C[C@@H](C)Oc3ncccc3S2(=O)=O)c1 |r| Show InChI InChI=1S/C28H31N5O5S/c1-5-33-24-11-10-22(19(4)27(24)30-31-33)23(14-26(34)35)20-9-8-17(2)21(13-20)16-32-15-18(3)38-28-25(39(32,36)37)7-6-12-29-28/h6-13,18,23H,5,14-16H2,1-4H3,(H,34,35)/t18-,23?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Intellectual Property Development Limited; Astex Therapeutics, Ltd US Patent					Assay Description 100 nL of 100× compound dose response curves (serial 3-fold dilutions) in DMSO are stamped using an Echo liquid handling system (Labcyte) into 384-we...				US Patent US10144731 (2018) BindingDB Entry DOI: 10.7270/Q25X2C17
					More data for this Ligand-Target Pair
Nuclear factor erythroid 2-related factor 2 (Homo sapiens (Human))	BDBM304752 (3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl...) Show SMILES CCn1nnc2c(C)c(ccc12)C(CC(O)=O)c1ccc(C)c(CN2C[C@@H](C)Oc3ncccc3S2(=O)=O)c1 |r| Show InChI InChI=1S/C28H31N5O5S/c1-5-33-24-11-10-22(19(4)27(24)30-31-33)23(14-26(34)35)20-9-8-17(2)21(13-20)16-32-15-18(3)38-28-25(39(32,36)37)7-6-12-29-28/h6-13,18,23H,5,14-16H2,1-4H3,(H,34,35)/t18-,23?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	550	n/a	n/a	n/a	n/a
GlaxoSmithKline Intellectual Property Development Limited; Astex Therapeutics, Ltd US Patent					Assay Description NAD(P)H:quinone oxidoreductase 1 (NQO1), also called DT diaphorase, is a homodimeric FAD-containing enzyme that catalyzes obligatory NAD(P)H-dependen...				US Patent US10144731 (2018) BindingDB Entry DOI: 10.7270/Q25X2C17
					More data for this Ligand-Target Pair