BindingDB logo
myBDB logout

null

SMILES: Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCC1CCOCC1)C(=O)NCCCc1ncc[nH]1

InChI Key: InChIKey=PZLJEJXZNDKQHK-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 306244   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nicotinamide phosphoribosyltransferase


(Homo sapiens (Human))		BDBM306244
PNG
(US10144742, Compound I-406)
Show SMILES Fc1ccc(cc1)-c1nc2cc(ccc2nc1OCC1CCOCC1)C(=O)NCCCc1ncc[nH]1
Show InChI InChI=1S/C27H28FN5O3/c28-21-6-3-19(4-7-21)25-27(36-17-18-9-14-35-15-10-18)33-22-8-5-20(16-23(22)32-25)26(34)31-11-1-2-24-29-12-13-30-24/h3-8,12-13,16,18H,1-2,9-11,14-15,17H2,(H,29,30)(H,31,34)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Millennium Pharmaceuticals, Inc.

US Patent


Assay Description
To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...

US Patent US10144742 (2018)


BindingDB Entry DOI: 10.7270/Q2NV9M91
More data for this
Ligand-Target Pair