BDBM307540 6-Ethoxy-2-(4-fluorophenyl)-N-methyl-5-(3-((1-(pyrimidin-2-yl)cyclopropyl) carbamoyl)phenyl)benzofuran-3-carboxamide::US10150747, Example 7

SMILES: CCOc1cc2oc(c(C(=O)NC)c2cc1-c1cccc(c1)C(=O)NC1(CC1)c1ncccn1)-c1ccc(F)cc1

InChI Key: InChIKey=ASJBLTSYOXKYPR-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 307540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA polymerase (NS5B) (Hepatitis C virus (HCV))	BDBM307540 (6-Ethoxy-2-(4-fluorophenyl)-N-methyl-5-(3-((1-(pyr...) Show SMILES CCOc1cc2oc(c(C(=O)NC)c2cc1-c1cccc(c1)C(=O)NC1(CC1)c1ncccn1)-c1ccc(F)cc1 Show InChI InChI=1S/C32H27FN4O4/c1-3-40-25-18-26-24(27(30(39)34-2)28(41-26)19-8-10-22(33)11-9-19)17-23(25)20-6-4-7-21(16-20)29(38)37-32(12-13-32)31-35-14-5-15-36-31/h4-11,14-18H,3,12-13H2,1-2H3,(H,34,39)(H,37,38)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...				US Patent US10150747 (2018) BindingDB Entry DOI: 10.7270/Q2H70HWJ
					More data for this Ligand-Target Pair
RNA polymerase (NS5B) (Hepatitis C virus (HCV))	BDBM307540 (6-Ethoxy-2-(4-fluorophenyl)-N-methyl-5-(3-((1-(pyr...) Show SMILES CCOc1cc2oc(c(C(=O)NC)c2cc1-c1cccc(c1)C(=O)NC1(CC1)c1ncccn1)-c1ccc(F)cc1 Show InChI InChI=1S/C32H27FN4O4/c1-3-40-25-18-26-24(27(30(39)34-2)28(41-26)19-8-10-22(33)11-9-19)17-23(25)20-6-4-7-21(16-20)29(38)37-32(12-13-32)31-35-14-5-15-36-31/h4-11,14-18H,3,12-13H2,1-2H3,(H,34,39)(H,37,38)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.78	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...				US Patent US10150747 (2018) BindingDB Entry DOI: 10.7270/Q2H70HWJ
					More data for this Ligand-Target Pair