null

SMILES: CCOc1cc2oc(c(C(=O)NC)c2cc1-c1ccc(CC)c(c1)C(=O)NC(C)(C)c1ncon1)-c1ccc(F)cc1

InChI Key: InChIKey=HJFODMYJWSCSHJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 307557   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus (HCV))	BDBM307557 (5-(3-((2-(1,2,4-oxadiazol-3-yl)propan-2-yl)carbamo...) Show SMILES CCOc1cc2oc(c(C(=O)NC)c2cc1-c1ccc(CC)c(c1)C(=O)NC(C)(C)c1ncon1)-c1ccc(F)cc1 Show InChI InChI=1S/C32H31FN4O5/c1-6-18-8-9-20(14-23(18)29(38)36-32(3,4)31-35-17-41-37-31)22-15-24-26(16-25(22)40-7-2)42-28(27(24)30(39)34-5)19-10-12-21(33)13-11-19/h8-17H,6-7H2,1-5H3,(H,34,39)(H,36,38)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...				US Patent US10150747 (2018) BindingDB Entry DOI: 10.7270/Q2H70HWJ
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV))	BDBM307557 (5-(3-((2-(1,2,4-oxadiazol-3-yl)propan-2-yl)carbamo...) Show SMILES CCOc1cc2oc(c(C(=O)NC)c2cc1-c1ccc(CC)c(c1)C(=O)NC(C)(C)c1ncon1)-c1ccc(F)cc1 Show InChI InChI=1S/C32H31FN4O5/c1-6-18-8-9-20(14-23(18)29(38)36-32(3,4)31-35-17-41-37-31)22-15-24-26(16-25(22)40-7-2)42-28(27(24)30(39)34-5)19-10-12-21(33)13-11-19/h8-17H,6-7H2,1-5H3,(H,34,39)(H,36,38)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...				US Patent US10150747 (2018) BindingDB Entry DOI: 10.7270/Q2H70HWJ
					More data for this Ligand-Target Pair