BDBM307701 (3R)-N-[5-chloro-4-(1-methyl-1H-benzimidazol-6-yl)pyridin-2-yl]piperidine-3-carboxamide::US9650358, Example 3

SMILES: Cn1cnc2ccc(cc12)-c1cc(NC(=O)[C@@H]2CCCNC2)ncc1Cl

InChI Key: InChIKey=MSMDWUISWULBMX-CYBMUJFWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307701   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM307701 ( (3R)-N-[5-chloro-4-(1-methyl-1H-benzimidazol-6-yl...) Show SMILES Cn1cnc2ccc(cc12)-c1cc(NC(=O)[C@@H]2CCCNC2)ncc1Cl Show InChI InChI=1S/C19H20ClN5O/c1-25-11-23-16-5-4-12(7-17(16)25)14-8-18(22-10-15(14)20)24-19(26)13-3-2-6-21-9-13/h4-5,7-8,10-11,13,21H,2-3,6,9H2,1H3,(H,22,24,26)/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9650358 (2017) BindingDB Entry DOI: 10.7270/Q2057J0M
					More data for this Ligand-Target Pair