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SMILES: NNC(=O)Cc1ccc(CCc2ccc(nc2)N2CCOCC2)cc1

InChI Key: InChIKey=ZGTHIWIAWAETDR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 309459   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM309459 (US9603833, Example 12) Show SMILES NNC(=O)Cc1ccc(CCc2ccc(nc2)N2CCOCC2)cc1 Show InChI InChI=1S/C19H24N4O2/c20-22-19(24)13-16-4-1-15(2-5-16)3-6-17-7-8-18(21-14-17)23-9-11-25-12-10-23/h1-2,4-5,7-8,14H,3,6,9-13,20H2,(H,22,24)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
R-Tech Ueno, Ltd. US Patent					Assay Description The compounds of the present invention obtained in Production Examples were examined for the inhibitory effect on human and rat VAP-1 enzyme (SSAO) b...				US Patent US9603833 (2017) BindingDB Entry DOI: 10.7270/Q2W37ZCW
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM309459 (US9603833, Example 12) Show SMILES NNC(=O)Cc1ccc(CCc2ccc(nc2)N2CCOCC2)cc1 Show InChI InChI=1S/C19H24N4O2/c20-22-19(24)13-16-4-1-15(2-5-16)3-6-17-7-8-18(21-14-17)23-9-11-25-12-10-23/h1-2,4-5,7-8,14H,3,6,9-13,20H2,(H,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.8	n/a	n/a	n/a	n/a	n/a	n/a
R-Tech Ueno, Ltd. US Patent					Assay Description The compounds of the present invention obtained in Production Examples were examined for the inhibitory effect on human and rat VAP-1 enzyme (SSAO) b...				US Patent US9603833 (2017) BindingDB Entry DOI: 10.7270/Q2W37ZCW
					More data for this Ligand-Target Pair