BDBM309981 (S)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-3-ethyl-1,2,4-oxadiazole-5-carboxamide::US9657003, 91
SMILES: CCc1noc(n1)C(=O)N[C@@H](C)Cn1ccc(n1)-c1ccc(C#N)c(Cl)c1
InChI Key: InChIKey=VPYVBXLWKNIYPX-NSHDSACASA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Androgen receptor (AR) (Homo sapiens (Human)) | BDBM309981![]() ((S)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ORION CORPORATION US Patent | Assay Description Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co... | US Patent US9657003 (2017) BindingDB Entry DOI: 10.7270/Q2NS0X0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (AR) (Homo sapiens (Human)) | BDBM309981![]() ((S)-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
ORION CORPORATION US Patent | Assay Description Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co... | US Patent US9657003 (2017) BindingDB Entry DOI: 10.7270/Q2NS0X0M | |||||||||||
More data for this Ligand-Target Pair |