BDBM309989 (S)-3-acetyl-N-(2-(3-(4-cyano-3,5-difluorophenyl)-1H-pyrazol-1-yl)propyl)-1H-pyrazole-5-carboxamide::US9657003, 219
SMILES: C[C@@H](CNC(=O)c1cc(n[nH]1)C(C)=O)n1ccc(n1)-c1cc(F)c(C#N)c(F)c1
InChI Key: InChIKey=MUSGLVPJRWGJAI-JTQLQIEISA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Androgen receptor (AR) (Homo sapiens (Human)) | BDBM309989![]() ((S)-3-acetyl-N-(2-(3-(4-cyano-3,5-difluorophenyl)-...) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ORION CORPORATION US Patent | Assay Description Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co... | US Patent US9657003 (2017) BindingDB Entry DOI: 10.7270/Q2NS0X0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (AR) (Homo sapiens (Human)) | BDBM309989![]() ((S)-3-acetyl-N-(2-(3-(4-cyano-3,5-difluorophenyl)-...) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 146 | n/a | n/a | n/a | n/a | n/a | n/a |
ORION CORPORATION US Patent | Assay Description Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co... | US Patent US9657003 (2017) BindingDB Entry DOI: 10.7270/Q2NS0X0M | |||||||||||
More data for this Ligand-Target Pair |