BDBM309990 (R)-N-(2-(3-(4-cyano-3,5-difluorophenyl)-1H-pyrazol-1-yl)propyl)-2-(cyanomethyl)thiazole-4-carboxamide::US9657003, 222
SMILES: C[C@H](CNC(=O)c1csc(CC#N)n1)n1ccc(n1)-c1cc(F)c(C#N)c(F)c1
InChI Key: InChIKey=NKDNPQJJLXRCBH-LLVKDONJSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Androgen receptor (AR) (Homo sapiens (Human)) | BDBM309990![]() ((R)-N-(2-(3-(4-cyano-3,5-difluorophenyl)-1H-pyrazo...) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ORION CORPORATION US Patent | Assay Description Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co... | US Patent US9657003 (2017) BindingDB Entry DOI: 10.7270/Q2NS0X0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (AR) (Homo sapiens (Human)) | BDBM309990![]() ((R)-N-(2-(3-(4-cyano-3,5-difluorophenyl)-1H-pyrazo...) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
ORION CORPORATION US Patent | Assay Description Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co... | US Patent US9657003 (2017) BindingDB Entry DOI: 10.7270/Q2NS0X0M | |||||||||||
More data for this Ligand-Target Pair |