BDBM309991 (S)-N-{1-[3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl]propan-2-yl}-2-methyl-1H-imidazole-4-carboxamide::US9657003, 248
SMILES: C[C@@H](Cn1ccc(n1)-c1ccc(C#N)c(Cl)c1)NC(=O)c1c[nH]c(C)n1
InChI Key: InChIKey=PEKHYHALXBZXQD-NSHDSACASA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Androgen receptor/Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM309991 ((S)-N-{1-[3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (AR) (Homo sapiens (Human)) | BDBM309991 ((S)-N-{1-[3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-...) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ORION CORPORATION US Patent | Assay Description Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co... | US Patent US9657003 (2017) BindingDB Entry DOI: 10.7270/Q2NS0X0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor/Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human)) | BDBM309991 ((S)-N-{1-[3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (AR) (Homo sapiens (Human)) | BDBM309991 ((S)-N-{1-[3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-...) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
ORION CORPORATION US Patent | Assay Description Androgen receptor (AR) binding affinities of test compounds were studied in cytosolic lysates obtained from ventral prostates of castrated rats by co... | US Patent US9657003 (2017) BindingDB Entry DOI: 10.7270/Q2NS0X0M | |||||||||||
More data for this Ligand-Target Pair |