BDBM310904 3-methoxy-N-[4-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl]propanamide::US10150767, Example 7

SMILES: COCCC(=O)Nc1ccc(cc1)-c1cn(C)c(=O)c2[nH]ccc12

InChI Key: InChIKey=IPDOQOMGRNAULI-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 310904   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cat eye syndrome critical region protein 2 [424-538] (Homo sapiens (Human))	BDBM310904 (3-methoxy-N-[4-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]py...) Show SMILES COCCC(=O)Nc1ccc(cc1)-c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C18H19N3O3/c1-21-11-15(14-7-9-19-17(14)18(21)23)12-3-5-13(6-4-12)20-16(22)8-10-24-2/h3-7,9,11,19H,8,10H2,1-2H3,(H,20,22)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc.; Constellation Pharmaceuticals Inc. US Patent					Assay Description His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...				US Patent US10150767 (2018) BindingDB Entry DOI: 10.7270/Q2V98B5W
					More data for this Ligand-Target Pair