BDBM310908 6-methyl-4-(4-(4-methyl-3-oxopiperazine-1-carbonyl)phenyl)-1H-pyrrolo[2,3-c]pyridin-7(6H)-one::US10150767, Example 26

SMILES: CN1CCN(CC1=O)C(=O)c1ccc(cc1)-c1cn(C)c(=O)c2[nH]ccc12

InChI Key: InChIKey=MPKJQOHTLSMADE-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 310908   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cat eye syndrome critical region protein 2 [424-538] (Homo sapiens (Human))	BDBM310908 (6-methyl-4-(4-(4-methyl-3-oxopiperazine-1-carbonyl...) Show SMILES CN1CCN(CC1=O)C(=O)c1ccc(cc1)-c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C20H20N4O3/c1-22-9-10-24(12-17(22)25)19(26)14-5-3-13(4-6-14)16-11-23(2)20(27)18-15(16)7-8-21-18/h3-8,11,21H,9-10,12H2,1-2H3	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc.; Constellation Pharmaceuticals Inc. US Patent					Assay Description His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...				US Patent US10150767 (2018) BindingDB Entry DOI: 10.7270/Q2V98B5W
					More data for this Ligand-Target Pair