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SMILES: Cn1cc(-c2ccc3CNCCc3c2)c2cc[nH]c2c1=O

InChI Key: InChIKey=MEPORSWHYAJTEV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 310911   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Chromatin remodeling regulator CECR2 [424-538]


(Homo sapiens (Human))		BDBM310911
PNG
(6-methyl-4-(2-methyl-3,4-dihydro-1H-isoquinolin-6-...)
Show SMILES Cn1cc(-c2ccc3CNCCc3c2)c2cc[nH]c2c1=O
Show InChI InChI=1S/C17H17N3O/c1-20-10-15(14-5-7-19-16(14)17(20)21)12-2-3-13-9-18-6-4-11(13)8-12/h2-3,5,7-8,10,18-19H,4,6,9H2,1H3
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 54n/an/an/an/an/an/a



Genentech, Inc.; Constellation Pharmaceuticals Inc.

US Patent


Assay Description
His/Flag epitope tagged CECR2424-538 was cloned, expressed, and purified to homogeneity. CECR2 binding and inhibition was assessed by monitoring the ...

US Patent US10150767 (2018)


BindingDB Entry DOI: 10.7270/Q2V98B5W
More data for this
Ligand-Target Pair