BDBM311139 example 3B.22 on page 219 of WO15017610

SMILES: C[C@@H](Oc1cc(cc2ncn(C)c12)-c1cnn(c1)C(C)(C)C)[C@H]1CNC(=O)C1

InChI Key: InChIKey=KSZAIPSQJXGBNH-UKRRQHHQSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 311139   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
SYK (aa 342-635) (Homo sapiens (Human))	BDBM311139 (example 3B.22 on page 219 of WO15017610) Show SMILES C[C@@H](Oc1cc(cc2ncn(C)c12)-c1cnn(c1)C(C)(C)C)[C@H]1CNC(=O)C1 |r| Show InChI InChI=1S/C21H27N5O2/c1-13(15-8-19(27)22-9-15)28-18-7-14(6-17-20(18)25(5)12-23-17)16-10-24-26(11-16)21(2,3)4/h6-7,10-13,15H,8-9H2,1-5H3,(H,22,27)/t13-,15-/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Recombinant human SYK (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag. The test compounds were dissolved in 100% D...				US Patent US10155751 (2018) BindingDB Entry DOI: 10.7270/Q2PK0J60
					More data for this Ligand-Target Pair
FLT3 (aa 564-960) (Homo sapiens (Human))	BDBM311139 (example 3B.22 on page 219 of WO15017610) Show SMILES C[C@@H](Oc1cc(cc2ncn(C)c12)-c1cnn(c1)C(C)(C)C)[C@H]1CNC(=O)C1 |r| Show InChI InChI=1S/C21H27N5O2/c1-13(15-8-19(27)22-9-15)28-18-7-14(6-17-20(18)25(5)12-23-17)16-10-24-26(11-16)21(2,3)4/h6-7,10-13,15H,8-9H2,1-5H3,(H,22,27)/t13-,15-/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	307	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Recombinant human FLT3 (amino acids 564-958, Molecular weight 48.6 kDa, Invitrogen #PR4666C) was expressed with an Histidine tag. The test compounds...				US Patent US10155751 (2018) BindingDB Entry DOI: 10.7270/Q2PK0J60
					More data for this Ligand-Target Pair
AURB (aa 1-341) (Homo sapiens (Human))	BDBM311139 (example 3B.22 on page 219 of WO15017610) Show SMILES C[C@@H](Oc1cc(cc2ncn(C)c12)-c1cnn(c1)C(C)(C)C)[C@H]1CNC(=O)C1 |r| Show InChI InChI=1S/C21H27N5O2/c1-13(15-8-19(27)22-9-15)28-18-7-14(6-17-20(18)25(5)12-23-17)16-10-24-26(11-16)21(2,3)4/h6-7,10-13,15H,8-9H2,1-5H3,(H,22,27)/t13-,15-/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	771	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Recombinant human Aurora B (amino acids 1-344, clone number DU1773, Molecular weight 40.2 kDa, University of Dundee) was expressed as a fusion protei...				US Patent US10155751 (2018) BindingDB Entry DOI: 10.7270/Q2PK0J60
					More data for this Ligand-Target Pair