null
SMILES: CC(C)C[C@H](N)COc1ccc(cc1F)-c1ccnc(NC(C)=O)c1
InChI Key: InChIKey=JJNHJOVVASIHIL-INIZCTEOSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AP2-associated protein kinase 1 (Mus musculus) | BDBM311153![]() ((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluoro...) | MMDB Reactome pathway B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | 0.520 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP2-associated protein kinase 1 (Homo sapiens (Human)) | BDBM311153![]() ((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluoro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi | Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra... | J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q2930WGG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP2-associated protein kinase 1 (Homo sapiens (Human)) | BDBM311153![]() ((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluoro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Co. US Patent | Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra... | US Patent US10351563 (2019) BindingDB Entry DOI: 10.7270/Q2P55QWS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP2-associated protein kinase 1 (Homo sapiens (Human)) | BDBM311153![]() ((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluoro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra... | US Patent US10544120 (2020) BindingDB Entry DOI: 10.7270/Q2RF5XCX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM311153![]() ((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluoro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | 8.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP2-associated protein kinase 1 (Homo sapiens (Human)) | BDBM311153![]() ((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluoro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 Cl prepared from 15 μl additions of enzyme and substrates (... | US Patent US10723734 (2020) BindingDB Entry DOI: 10.7270/Q2Z60S4P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP2-associated protein kinase 1 (Homo sapiens (Human)) | BDBM311153![]() ((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluoro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP2-associated protein kinase 1 (Homo sapiens (Human)) | BDBM311153![]() ((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluoro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP2-associated protein kinase 1 (Homo sapiens (Human)) | BDBM311153![]() ((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluoro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra... | US Patent US10155760 (2018) BindingDB Entry DOI: 10.7270/Q2F191S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP2-associated protein kinase 1 (Homo sapiens (Human)) | BDBM311153![]() ((S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluoro...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 Cl prepared from 15 μl additions of enzyme and substrates (... | US Patent US10723734 (2020) BindingDB Entry DOI: 10.7270/Q2Z60S4P | |||||||||||
More data for this Ligand-Target Pair |