null

SMILES: CS(=O)(=O)N1CCCC(C1)n1cc(NC(=O)c2cnn3ccc(N[C@H]4CCCC[C@H]4N)nc23)c(n1)C(N)=O

InChI Key: InChIKey=ROLVPPMVMFARPG-XMKPYSNPSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311532   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM311532 (5-{[cis-2- aminocyclohexyl]amino}- N-{3-carbamoyl-...) Show SMILES CS(=O)(=O)N1CCCC(C1)n1cc(NC(=O)c2cnn3ccc(N[C@H]4CCCC[C@H]4N)nc23)c(n1)C(N)=O |r| Show InChI InChI=1S/C23H32N10O4S/c1-38(36,37)31-9-4-5-14(12-31)33-13-18(20(30-33)21(25)34)28-23(35)15-11-26-32-10-8-19(29-22(15)32)27-17-7-3-2-6-16(17)24/h8,10-11,13-14,16-17H,2-7,9,12,24H2,1H3,(H2,25,34)(H,27,29)(H,28,35)/t14?,16-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...				US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J
					More data for this Ligand-Target Pair