BDBM31174 CHEMBL29757::D-Aspartate::D-Aspartic Acid

SMILES: N[C@H](CC(O)=O)C(O)=O

InChI Key: InChIKey=CKLJMWTZIZZHCS-UWTATZPHSA-N

Data: 3 KI  1 Kd  3 EC50

PDB links: 81 PDB IDs match this monomer. 5 PDB IDs contain this monomer as substructures. 5 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 31174   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM31174 (CHEMBL29757 | D-Aspartate | D-Aspartic Acid) Show SMILES N[C@H](CC(O)=O)C(O)=O Show InChI InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by PDSP Ki Database									Br J Pharmacol 95: 932-8 (1988) Article DOI: 10.1111/j.1476-5381.1988.tb11723.x BindingDB Entry DOI: 10.7270/Q2Z036NF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM31174 (CHEMBL29757 | D-Aspartate | D-Aspartic Acid) Show SMILES N[C@H](CC(O)=O)C(O)=O Show InChI InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY Corporation Curated by PDSP Ki Database									Br J Pharmacol 95: 932-8 (1988) Article DOI: 10.1111/j.1476-5381.1988.tb11723.x BindingDB Entry DOI: 10.7270/Q2Z036NF
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM31174 (CHEMBL29757 | D-Aspartate | D-Aspartic Acid) Show SMILES N[C@H](CC(O)=O)C(O)=O Show InChI InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by PDSP Ki Database									Biochemistry 24: 2401-5 (1985) Article DOI: 10.1021/bi00331a002 BindingDB Entry DOI: 10.7270/Q2W094FK
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM31174 (CHEMBL29757 | D-Aspartate | D-Aspartic Acid) Show SMILES N[C@H](CC(O)=O)C(O)=O Show InChI InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonistic activity at mGlu1-alpha receptor expressed in CHO cells				J Med Chem 39: 3188-94 (1996) Article DOI: 10.1021/jm9602569 BindingDB Entry DOI: 10.7270/Q2M909BH
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM31174 (CHEMBL29757 | D-Aspartate | D-Aspartic Acid) Show SMILES N[C@H](CC(O)=O)C(O)=O Show InChI InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonistic activity at mGlu2 receptor expressed in CHO cells				J Med Chem 39: 3188-94 (1996) Article DOI: 10.1021/jm9602569 BindingDB Entry DOI: 10.7270/Q2M909BH
					More data for this Ligand-Target Pair
Glutamate transporter homolog (Pyrococcus horikoshii (strain ATCC 700860 / DSM 12...)	BDBM31174 (CHEMBL29757 | D-Aspartate | D-Aspartic Acid) Show SMILES N[C@H](CC(O)=O)C(O)=O Show InChI InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
Columbia University Curated by ChEMBL					Assay Description Binding affinity to Pyrococcus horikoshii sodium-coupled aspartate transporter L130W mutant fluorescence-based assay in presence of NaCl				Nature 445: 387-93 (2007) Article DOI: 10.1038/nature05455 BindingDB Entry DOI: 10.7270/Q29C716Z
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Homo sapiens (Human))	BDBM31174 (CHEMBL29757 | D-Aspartate | D-Aspartic Acid) Show SMILES N[C@H](CC(O)=O)C(O)=O Show InChI InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonistic activity at mGlu6 receptor expressed in CHO cells				J Med Chem 39: 3188-94 (1996) Article DOI: 10.1021/jm9602569 BindingDB Entry DOI: 10.7270/Q2M909BH
					More data for this Ligand-Target Pair