null

SMILES: NC(=O)c1ncccc1NC(=O)c1cnn2cccnc12

InChI Key: InChIKey=FQQLYADVQADJOU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312066   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human))	BDBM312066 (N-(2-Carbamoylpyridin-3-yl)pyrazolo[1,5-a]pyrimidi...) Show SMILES NC(=O)c1ncccc1NC(=O)c1cnn2cccnc12 Show InChI InChI=1S/C13H10N6O2/c14-11(20)10-9(3-1-4-15-10)18-13(21)8-7-17-19-6-2-5-16-12(8)19/h1-7H,(H2,14,20)(H,18,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...				US Patent US10155765 (2018) BindingDB Entry DOI: 10.7270/Q21V5H2J
					More data for this Ligand-Target Pair