BDBM31566 oxadiazole derivative, 20f

SMILES: Clc1ccc(CSc2nnc(o2)-c2ccc3OCCc3c2)cc1

InChI Key: InChIKey=IMCYIKQGNHUSRD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM31566 (oxadiazole derivative, 20f) Show SMILES Clc1ccc(CSc2nnc(o2)-c2ccc3OCCc3c2)cc1 Show InChI InChI=1S/C17H13ClN2O2S/c18-14-4-1-11(2-5-14)10-23-17-20-19-16(22-17)13-3-6-15-12(9-13)7-8-21-15/h1-6,9H,7-8,10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	7.5	37
Takeda Pharmaceutical Company Ltd.					Assay Description Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...				Bioorg Med Chem 17: 2017-29 (2009) Article DOI: 10.1016/j.bmc.2009.01.019 BindingDB Entry DOI: 10.7270/Q2DR2STZ
					More data for this Ligand-Target Pair