BDBM31731 4-[5-[(Z)-(1-ketothiazolo[3,2-a]benzimidazol-2-ylidene)methyl]-2-furyl]benzoic acid::4-[5-[(Z)-(1-oxidanylidene-[1,3]thiazolo[3,2-a]benzimidazol-2-ylidene)methyl]furan-2-yl]benzoic acid::4-[5-[(Z)-(1-oxo-2-thiazolo[3,2-a]benzimidazolylidene)methyl]-2-furanyl]benzoic acid::4-[5-[(Z)-(1-oxo-[1,3]thiazolo[3,2-a]benzimidazol-2-ylidene)methyl]furan-2-yl]benzoic acid::MLS-0091939.0001::cid_2243732

SMILES: OC(=O)c1ccc(cc1)-c1ccc(\C=c2/sc3nc4ccccc4n3c2=O)o1

InChI Key: InChIKey=PBRCPUKRPJYRTF-WQRHYEAKSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 31731   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MKP-3 (Rattus norvegicus)	BDBM31731 (4-[5-[(Z)-(1-ketothiazolo[3,2-a]benzimidazol-2-yli...) Show SMILES OC(=O)c1ccc(cc1)-c1ccc(\C=c2/sc3nc4ccccc4n3c2=O)o1 Show InChI InChI=1S/C21H12N2O4S/c24-19-18(28-21-22-15-3-1-2-4-16(15)23(19)21)11-14-9-10-17(27-14)12-5-7-13(8-6-12)20(25)26/h1-11H,(H,25,26)/b18-11-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	7.0	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Burnham Center for Chemical Genomics (BCCG) Source Affiliation: Burnham Institute for Medical Research (BIMR, La Jolla, CA) Network: NIH...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2N87841
					More data for this Ligand-Target Pair
MKP-3 (Rattus norvegicus)	BDBM31731 (4-[5-[(Z)-(1-ketothiazolo[3,2-a]benzimidazol-2-yli...) Show SMILES OC(=O)c1ccc(cc1)-c1ccc(\C=c2/sc3nc4ccccc4n3c2=O)o1 Show InChI InChI=1S/C21H12N2O4S/c24-19-18(28-21-22-15-3-1-2-4-16(15)23(19)21)11-14-9-10-17(27-14)12-5-7-13(8-6-12)20(25)26/h1-11H,(H,25,26)/b18-11-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q25H7DPX
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase (VHR) (Homo sapiens (Human))	BDBM31731 (4-[5-[(Z)-(1-ketothiazolo[3,2-a]benzimidazol-2-yli...) Show SMILES OC(=O)c1ccc(cc1)-c1ccc(\C=c2/sc3nc4ccccc4n3c2=O)o1 Show InChI InChI=1S/C21H12N2O4S/c24-19-18(28-21-22-15-3-1-2-4-16(15)23(19)21)11-14-9-10-17(27-14)12-5-7-13(8-6-12)20(25)26/h1-11H,(H,25,26)/b18-11-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	6.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2WW7G20
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase (VHR) (Homo sapiens (Human))	BDBM31731 (4-[5-[(Z)-(1-ketothiazolo[3,2-a]benzimidazol-2-yli...) Show SMILES OC(=O)c1ccc(cc1)-c1ccc(\C=c2/sc3nc4ccccc4n3c2=O)o1 Show InChI InChI=1S/C21H12N2O4S/c24-19-18(28-21-22-15-3-1-2-4-16(15)23(19)21)11-14-9-10-17(27-14)12-5-7-13(8-6-12)20(25)26/h1-11H,(H,25,26)/b18-11-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	3.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DB807Z
					More data for this Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM31731 (4-[5-[(Z)-(1-ketothiazolo[3,2-a]benzimidazol-2-yli...) Show SMILES OC(=O)c1ccc(cc1)-c1ccc(\C=c2/sc3nc4ccccc4n3c2=O)o1 Show InChI InChI=1S/C21H12N2O4S/c24-19-18(28-21-22-15-3-1-2-4-16(15)23(19)21)11-14-9-10-17(27-14)12-5-7-13(8-6-12)20(25)26/h1-11H,(H,25,26)/b18-11-	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	5.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q21N7ZJW
					More data for this Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM31731 (4-[5-[(Z)-(1-ketothiazolo[3,2-a]benzimidazol-2-yli...) Show SMILES OC(=O)c1ccc(cc1)-c1ccc(\C=c2/sc3nc4ccccc4n3c2=O)o1 Show InChI InChI=1S/C21H12N2O4S/c24-19-18(28-21-22-15-3-1-2-4-16(15)23(19)21)11-14-9-10-17(27-14)12-5-7-13(8-6-12)20(25)26/h1-11H,(H,25,26)/b18-11-	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2474894
					More data for this Ligand-Target Pair