BDBM31938 1,3-thiazolidin-5-ylidene derivative, 4b
SMILES: COCCN1C(=O)\C(S\C1=N\c1ccccc1)=C/c1ccc(o1)-c1ccc(Cl)cc1
InChI Key: InChIKey=ZDKZIFJIVAQYPG-DIRPYQRSSA-N
Data: 1 Other
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) (Helicobacter pylori (Campylobacter pylori)) | BDBM31938 (1,3-thiazolidin-5-ylidene derivative, 4b) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | 25 |
Shanghai Institute of Materia Medica | Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr... | J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W | |||||||||||
More data for this Ligand-Target Pair |