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BDBM31949 1,3-thiazolidin-5-ylidene derivative, 4m

SMILES: COCCN1C(=O)\C(S\C1=N\c1cccc(c1)C(F)(F)F)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(=O)OC

InChI Key: InChIKey=UPPDXTHVEGOCMN-GEUTYLJLSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31949   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ)


(Helicobacter pylori (Campylobacter pylori))		BDBM31949
PNG
(1,3-thiazolidin-5-ylidene derivative, 4m)
Show SMILES COCCN1C(=O)\C(S\C1=N\c1cccc(c1)C(F)(F)F)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(=O)OC
Show InChI InChI=1S/C26H20ClF3N2O5S/c1-35-11-10-32-23(33)22(38-25(32)31-17-5-3-4-16(13-17)26(28,29)30)14-18-7-9-21(37-18)15-6-8-20(27)19(12-15)24(34)36-2/h3-9,12-14H,10-11H2,1-2H3/b22-14+,31-25+
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/an/an/an/an/an/a



Shanghai Institute of Materia Medica



Assay Description
The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...

J Med Chem 52: 2465-81 (2009)


Article DOI: 10.1021/jm8015602
BindingDB Entry DOI: 10.7270/Q2ZK5F1W
More data for this
Ligand-Target Pair