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BDBM31956 1,3-thiazolidin-5-ylidene derivative, 4t

SMILES: CCN(CC)CCN1C(=O)\C(S\C1=N\c1ccccc1)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(=O)OC

InChI Key: InChIKey=WOVRDFQOZBWEQF-OUCSHJNUSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31956   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ)


(Helicobacter pylori (Campylobacter pylori))		BDBM31956
PNG
(1,3-thiazolidin-5-ylidene derivative, 4t)
Show SMILES CCN(CC)CCN1C(=O)\C(S\C1=N\c1ccccc1)=C/c1ccc(o1)-c1ccc(Cl)c(c1)C(=O)OC
Show InChI InChI=1S/C28H28ClN3O4S/c1-4-31(5-2)15-16-32-26(33)25(37-28(32)30-20-9-7-6-8-10-20)18-21-12-14-24(36-21)19-11-13-23(29)22(17-19)27(34)35-3/h6-14,17-18H,4-5,15-16H2,1-3H3/b25-18+,30-28+
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PC cid
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UniChem

Similars
Article
PubMed
n/an/an/an/an/an/an/an/an/a



Shanghai Institute of Materia Medica



Assay Description
The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...

J Med Chem 52: 2465-81 (2009)


Article DOI: 10.1021/jm8015602
BindingDB Entry DOI: 10.7270/Q2ZK5F1W
More data for this
Ligand-Target Pair