BDBM319641 4-[5-(trifluoromethyl)-1H-1,2,3-triazol-4-yl]-2- (1-{2-[2-(trifluoromethyl)phenyl]ethyl}-1H- imidazol-4-yl)pyridine::US10174003, Example 60::US9896436, Example 60

SMILES: FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2ccccc2C(F)(F)F)cn1

InChI Key: InChIKey=IQXPWKHDTIHLLB-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 319641   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319641 (4-[5-(trifluoromethyl)-1H-1,2,3-triazol-4-yl]-2- (...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2ccccc2C(F)(F)F)cn1 Show InChI InChI=1S/C20H14F6N6/c21-19(22,23)14-4-2-1-3-12(14)6-8-32-10-16(28-11-32)15-9-13(5-7-27-15)17-18(20(24,25)26)30-31-29-17/h1-5,7,9-11H,6,8H2,(H,29,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10174003 (2019) BindingDB Entry DOI: 10.7270/Q2417053
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319641 (4-[5-(trifluoromethyl)-1H-1,2,3-triazol-4-yl]-2- (...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2ccccc2C(F)(F)F)cn1 Show InChI InChI=1S/C20H14F6N6/c21-19(22,23)14-4-2-1-3-12(14)6-8-32-10-16(28-11-32)15-9-13(5-7-27-15)17-18(20(24,25)26)30-31-29-17/h1-5,7,9-11H,6,8H2,(H,29,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				US Patent US10174003 (2019) BindingDB Entry DOI: 10.7270/Q2417053
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM319641 (4-[5-(trifluoromethyl)-1H-1,2,3-triazol-4-yl]-2- (...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2ccccc2C(F)(F)F)cn1 Show InChI InChI=1S/C20H14F6N6/c21-19(22,23)14-4-2-1-3-12(14)6-8-32-10-16(28-11-32)15-9-13(5-7-27-15)17-18(20(24,25)26)30-31-29-17/h1-5,7,9-11H,6,8H2,(H,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319641 (4-[5-(trifluoromethyl)-1H-1,2,3-triazol-4-yl]-2- (...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2ccccc2C(F)(F)F)cn1 Show InChI InChI=1S/C20H14F6N6/c21-19(22,23)14-4-2-1-3-12(14)6-8-32-10-16(28-11-32)15-9-13(5-7-27-15)17-18(20(24,25)26)30-31-29-17/h1-5,7,9-11H,6,8H2,(H,29,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM319641 (4-[5-(trifluoromethyl)-1H-1,2,3-triazol-4-yl]-2- (...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2ccccc2C(F)(F)F)cn1 Show InChI InChI=1S/C20H14F6N6/c21-19(22,23)14-4-2-1-3-12(14)6-8-32-10-16(28-11-32)15-9-13(5-7-27-15)17-18(20(24,25)26)30-31-29-17/h1-5,7,9-11H,6,8H2,(H,29,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				Bioorg Med Chem Lett 17: 1584-9 (2007) BindingDB Entry DOI: 10.7270/Q2FT8PBQ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM319641 (4-[5-(trifluoromethyl)-1H-1,2,3-triazol-4-yl]-2- (...) Show SMILES FC(F)(F)c1[nH]nnc1-c1ccnc(c1)-c1cn(CCc2ccccc2C(F)(F)F)cn1 Show InChI InChI=1S/C20H14F6N6/c21-19(22,23)14-4-2-1-3-12(14)6-8-32-10-16(28-11-32)15-9-13(5-7-27-15)17-18(20(24,25)26)30-31-29-17/h1-5,7,9-11H,6,8H2,(H,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10174003 (2019) BindingDB Entry DOI: 10.7270/Q2417053
					More data for this Ligand-Target Pair